2.19.2018

Penelitian Air Alkali pada Kanker

PENELITIAN AIR ALKALI PADA KANKER & TERAPI KANKER

Sahabat yang Amazing....
Banyak sekali penelitian yang menunjukkan bahwa air alkali memiliki manfaat yang luas pada penyakit kanker. Berikut ini beberapa penelitiannya. Nomor di awal penelitian merupakan nomor penelitian di situs Molecular Hydrogen Foundation, salah satu organisasi ilmiah yang khusus mengkaji mengenai manfaat air alkali pada berbagai penyakit pada manusia (www.molecularhydrogenfoundation.org).

EFEK PENCEGAHAN & EFEK ANTI KANKER
97.LEE, K.-J., et al., Anticancer Effect of Alkaline Reduced Water. J Int Soc Life Inf Sci, 2004. 22(2): p. 302-305.

95.Kinjo, T., et al., Suppressive effects of electrochemically reduced water on matrix metalloproteinase-2 activities and in vitro invasion of human fibrosarcoma HT1080 cells. Cytotechnology, 2012. 64(3): p. 357-371.

91.Akio Kagawa, K.K., Masayuki Mizumoto, Yutaka Tagawa, Yoichi Masiko, Influence of Hydrogen Discharged from Palladium Base Hydrogen Storage Alloys on Cancer Cells. Materials Science Forum, 2012. 706: p. 520-525.

96.Komatsu, T., Katakura, Y., Teruya, K., Otsubo, K., Morisawa, S., & and S. Shirahata, Electrolyzed reduced water induces differentiation in K-562 human leukemia cells. Animal cell technology: Basic & applied aspects, 2003: p. 387-391.

423.Kawai, D., et al., Hydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice. Hepatology, 2012. 56(3): p. 912-21.

111.Saitoh, Y., et al., Platinum nanocolloid-supplemented hydrogen dissolved water inhibits growth of human tongue carcinoma cells preferentially over normal cells. Exp Oncol, 2009. 31(3): p. 156-62.

112.Tsai, C.F., et al., Enhanced induction of mitochondrial damage and apoptosis in human leukemia HL-60 cells due to electrolyzed-reduced water and glutathione. Biosci Biotechnol Biochem, 2009. 73(2): p. 280-7.

107.Roberts, B.J., et al., Response of five established solid transplantable mouse tumors and one mouse leukemia to hyperbaric hydrogen. Cancer Treat Rep, 1978. 62(7): p. 1077-9.

424.Kim, H.-W., Alkaline Reduced Water produced by UMQ showed Anti-cancer and Anti-diabetic effect. published online at http://www.korea-water.com/images/e_q.pdf 2004.

91.Asada, R., et al., Antitumor effects of nano-bubble hydrogen-dissolved water are enhanced by coexistent platinum colloid and the combined hyperthermia with apoptosis-like cell death. Oncol Rep, 2010. 24(6): p. 1463-70.

93.Dole, M., F.R. Wilson, and W.P. Fife, Hyperbaric hydrogen therapy: a possible treatment for cancer. Science, 1975. 190(4210): p. 152-4.

99.Matsuzaki, M., et al., Mechanism of Cancer Cell Death Induced by Hydrogen Discharged from Palladium Base Hydrogen Storage Alloy, in Materials Science and Chemical Engineering 2013. p. 284-290.

100.Motoishi, A., et al., Influence of Active Hydrogen Discharged from Palladium-Nickel Alloy Powder on Biological Cells. Advanced Materials Research, 2013. 669: p. 273-278.

101.Nakanishi, K., et al., Growth suppression of HL60 and L6 cells by atomic hydrogen, in Animal Cell Technology: Basic & Applied Aspects, . 2010, Springer Netherlands. p. 323-325.

110.Saitoh, Y., et al., Neutral pH Hydrogen-Enriched Electrolyzed Water Achieves Tumor-Preferential Clonal Growth Inhibition Over Normal Cells and Tumor Invasion Inhibition Concurrently With Intracellular Oxidant Repression. Oncology Research, 2008. 17(6): p. 247-255.

455.Li, F.Y., et al., Consumption of hydrogen-rich water protects against ferric nitrilotriacetate-induced nephrotoxicity and early tumor promotional events in rats. Food Chem Toxicol, 2013. 61: p. 248-54.

EFEK PADA INVASI, PENYEBARAN (METASTASIS) & ANGIOGENESIS KANKER
94.Jun, Y., et al., Suppression of invasion of cancer cells and angiogenesis by electrolyzed reduced water. In Vitro Cellular & Developmental Biology-Animal, 2004. 40: p. 79A-79A.

95.Kinjo, T., et al., Suppressive effects of electrochemically reduced water on matrix metalloproteinase-2 activities and in vitro invasion of human fibrosarcoma HT1080 cells. Cytotechnology, 2012. 64(3): p. 357-371.

110.Saitoh, Y., et al., Neutral pH Hydrogen-Enriched Electrolyzed Water Achieves Tumor-Preferential Clonal Growth Inhibition Over Normal Cells and Tumor Invasion Inhibition Concurrently With Intracellular Oxidant Repression. Oncology Research, 2008. 17(6): p. 247-255.

113.Ye, J., et al., Inhibitory effect of electrolyzed reduced water on tumor angiogenesis. Biological & Pharmaceutical Bulletin, 2008. 31(1): p. 19-26.

MENINGKATKAN KEAMANAN & KEBERHASILAN KEMOTERAPI
108.Runtuwene, J., et al., Hydrogen-water enhances 5-fluorouracil-induced inhibition of colon cancer. PeerJ, 2015. 3: p. e859.

102.Nakashima-Kamimura, N., et al., Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice. Cancer Chemother Pharmacol, 2009.

98.Matsushita, T., et al., Investigation of protective effect of hydrogen-rich water against cisplatin-induced nephrotoxicity in rats using blood oxygenation level-dependent magnetic resonance imaging. Jpn J Radiol, 2011. 29(7): p. 503-12.

102.Nakashima-Kamimura, N., et al., Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice. Cancer Chemother Pharmacol, 2009.

344.Kitamura, A., et al., Experimental verification of protective effect of hydrogen-rich water against cisplatin-induced nephrotoxicity in rats using dynamic contrast-enhanced CT. British Journal of Radiology, 2010. 83(990): p. 509-514.

124.Qu, J., et al., Inhalation of hydrogen gas attenuates cisplatin-induced ototoxicity via reducing oxidative stress. Int J Pediatr Otorhinolaryngol, 2012. 76(1): p. 111-5.

MENINGKATKAN KEBERHASILAN & KEAMANAN RADIOTERAPI
183.Chuai, Y., et al., Molecular hydrogen and radiation protection. Free Radical Research, 2012. 46(9): p. 1061-7.

273.Kang, K.-M., et al., Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors. Medical Gas Research, 2011. 1: p. 11.

201.Liu, C., et al., Hydrogen therapy may be an effective and specific novel treatment for acute radiation syndrome.Medical Hypotheses, 2010. 74(1): p. 145-146.

218.Qian, L., et al., The potential cardioprotective effects of hydrogen in irradiated mice. J Radiat Res, 2010. 51(6): p. 741-7.

219.Qian, L., et al., Hydrogen as a New Class of Radioprotective Agent. International journal of biological sciences, 2013. 9(9): p. 887-894.

220.Qian, L.R., et al., The Hypothesis of an Effective Safe and Novel Radioprotective Agent Hydrogen-rich Solution.West Indian Medical Journal, 2010. 59(2): p. 122-124.

66.Mei, K., et al., Hydrogen protects rats from dermatitis caused by local radiation. J Dermatolog Treat, 2014. 25(2): p. 182-8.

517.Chuai, Y., et al., Hydrogen-rich saline attenuates radiation-induced male germ cell loss in mice through reducing hydroxyl radicals. Biochemical Journal, 2012. 442(1): p. 49-56.

527.Qian, L.R., et al., Radioprotective effect of hydrogen in cultured cells and mice. Free Radic Res, 2010. 44(3): p. 275-282.

528.Qian, L.R., et al., Hydrogen-rich PBS protects cultured human cells from ionizing radiation-induced cellular damage. Nuclear Technology & Radiation Protection, 2010. 25(1): p. 23-29.

532.Yang, Y., et al., Molecular hydrogen protects human lymphocyte AHH-1 cells against C heavy ion radiation.International Journal of Radiation Biology, 2013.

533.Yoon, K.S., et al., Histological study on the effect of electrolyzed reduced water-bathing on UVB radiation-induced skin injury in hairless mice. Biological and Pharmaceutical Bulletin, 2011. 34(11): p. 1671-7.

536.Zhao, L., et al., Hydrogen protects mice from radiation induced thymic lymphoma in BALB/c mice. International Journal of Biological Sciences, 2011. 7(3): p. 297-300.

537.Zhao, S., et al., Protective effect of hydrogen-rich saline against radiation-induced immune dysfunction. J Cell Mol Med, 2014. 18(5): p. 938-46

66.Mei, K., et al., Hydrogen protects rats from dermatitis caused by local radiation. J Dermatolog Treat, 2014. 25(2): p. 182-8.

Keramati Yazdi F et al. Radioprotective effect of Zamzam (alkaline) water: A cytogenetic study. J Environ Radioact. 2016 Nov 10. pii: S0265-931X(16)30330-7. doi:10.1016/j.jenvrad.2016.10.019.

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Sumber: dr.AndipratamaDharma,SpPD
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